PREGNANCY and BREAST-FEEDING: It is not known if Imitrex tablets can cause harm to the fetus. If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Imitrex tablets while you are pregnant. Imitrex tablets are found in breast milk. If you are or will be breast-feeding while you use Imitrex tablets, check with your doctor. Discuss any possible risks to your baby. Techniques to stop negative thoughts. Six of these 8 patients had ECG changes consistent with transient ischemia, but without accompanying clinical symptoms or signs. Of these 8 patients, 4 had either findings suggestive of CAD or risk factors predictive of CAD prior to study enrollment.
IMITREX. See the end of this leaflet for a complete list of ingredients in IMITREX. Take this medication only as needed when a migraine occurs, as directed by your doctor. This medication should not be taken on a regular schedule. Never increase your dose of this medication or take it more often than prescribed by your doctor. In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.
Different brands of this have differentstorage needs. Your healthcare provider may change your dose. Do not change your dose without first talking with your healthcare provider. Ask your healthcare provider if you should take your first dose in a medical setting. USP in water for injection, USP. These are not all the possible side effects of IMITREX.
AUC corresponding to a 40% increase in elimination half-life. IMITREX Injection is administered to treat any subsequent attacks. Incidence in Controlled Trials of Cluster Headache: In the controlled clinical trials assessing sumatriptan's efficacy as a treatment for cluster headache, no new significant adverse events associated with the use of sumatriptan were detected that had not already been identified in association with the drug's use in migraine. Tell your doctor all medications and supplements you use. Tell your doctor if you are pregnant or plan to become pregnant while using Imitrex Injection. It is unknown if Imitrex Injection will harm a fetus. Your name may need to be listed on a sumatriptan pregnancy registry when you start using Imitrex Injection. Imitrex Injection can pass into breast milk and may harm a nursing baby. Do not breastfeed within 12 hours after using Imitrex Injection. If you use a breast pump during this time, throw out any milk you collect. Do not feed it to your baby.
Product Information. Imitrex nasal spray sumatriptan. Cardiac events that have been observed to have onset within 1 hour of sumatriptan administration include: coronary artery vasospasm, transient ischemia, myocardial infarction, ventricular tachycardia and ventricular fibrillation, cardiac arrest, and death. Because clinical trials are conducted under widely varying conditions, adverse reaction rates observed in the clinical trials of a drug cannot be directly compared with rates in the clinical trials of another drug and may not reflect the rates observed in practice. If you are at high risk for heart disease, your doctor may want to check your heart before prescribing sumatriptan. Increase in Blood Pressure: Significant elevation in blood pressure, including hypertensive crisis, has been reported on rare occasions in patients with and without a history of hypertension. Sumatriptan is contraindicated in patients with uncontrolled hypertension see . Sumatriptan should be administered with caution to patients with controlled hypertension as transient increases in blood pressure and peripheral vascular resistance have been observed in a small proportion of patients. Imitrex Nasal Spray sumatriptan Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication. Choose and Prepare the Injection Site. Hold the Pen by the ridges at the top. Plasma exposure at the lowest dose tested was approximately 2 times that in humans at the MRHD. IMITREX can cause dizziness, weakness, or drowsiness. If you have these symptoms, do not drive a car, use machinery, or do anything where you need to be alert.
Use: For the acute treatment of cluster headache. Take the Pen out of the Carrying Case. What should I tell my healthcare provider before taking IMITREX? IMITREX injections may have worse headaches medication overuse headache. About FAERS: The FDA Adverse Event Reporting System FAERS is used by FDA for activities such as looking for new safety concerns that might be related to a marketed product, evaluating a manufacturer's compliance to reporting regulations and responding to outside requests for information. Reporting of adverse events is a voluntary process, and not every report is sent to FDA and entered into FAERS. danocrine
A. Throw away the seal. Open the lid over the Syringe Cartridge. Tell your doctor if you are or if you plan to become pregnant. The Pen is now ready to use. You may find that combining a triptan with a nonprescription medicine such as or helps to stop your headaches better. Talk to your doctor about this option if triptans alone aren't helping enough. Sumatriptan may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be alert. The most successful ways to treat the pain are a shot of and breathing oxygen through a face mask for 20 minutes. Other drugs used for migraines called triptans may work. Prescription medicines based on the ergot and nasal spray might also help. Many people using this medication not have serious side effects. Luman W, Gray RS "Adverse reactions associated with sumatriptan. To recall numbers, group them and then relate them to a date or story. shop alfuzosin kit alfuzosin
This drug may make you dizzy or drowsy. not drive, use machinery, or do any activity that requires alertness until you are sure you can perform such activities safely. Avoid beverages. Sumatriptan belongs to a group of drugs called triptans. Some people who use too many Imitrex tablets may have worse headaches medication overuse headache. If your headaches get worse, your healthcare provider may decide to stop your treatment with Imitrex. Store at room temperature away from light and moisture. not store in the bathroom. Keep all away from children and pets. Eye: Accommodation disorders, blindness and low vision, conjunctivitis, disorders of sclera, external ocular muscle disorders, eye edema and swelling, eye hemorrhage, eye itching, eye pain, keratitis, mydriasis, and visual disturbances. This year, I finally went to a doctor because I was tired of my migraines controlling my life. She first gave me the sumatriptan pills 10 mg at first, then 20 mg but it didn't stop the vomiting. Therefore, I couldn't keep the medicine down long enough for it to start working. So, she prescribed me the nasal spray. When I took the first dose, I was a little worried that I wouldn't take it correctly. The directions made it seem so complicated. I also didn't realize how AWFUL it would taste, so I thought I had taken too many deep breaths or something after inhaling it. It took about 2 hours before my headache was completely gone. The migraine was pretty intense, but I didn't vomit at all, which surprised me. So I think the nasal spray does work. Sure, it's not as easy as the pill, but if it stops the vomiting and completely gets rid of my migraine, I'm happy. Ottervanger JP, van Witsen TB, Valkenburg HA, Stricker BH "Postmarketing study of cardiovascular adverse reactions associated with sumatriptan. Pen as shown in Figure B before you load a new Syringe Cartridge.
Sumatriptan succinate is a white to off-white powder that is readily soluble in water and in saline. Pale or blue-colored hands or feet. HGPRT, chromosomal aberration in human lymphocytes and in vivo rat micronucleus assays. Studies 2 and 3 the onset of relief was less than 10 minutes. Headache relief, as defined by a reduction in pain from severe or moderately severe to mild or no headache, was achieved in 70% of the patients within 1 hour of a single 6-mg subcutaneous dose of Imitrex Injection. Approximately 82% and 65% of patients treated with IMITREX 6 mg had headache relief and were pain free within 2 hours, respectively. Do not share this medication with others. There were no differences in relief rates at 60 minutes postdose for IMITREX Injection, whether or not prophylactic medications were used. Imitrex tablets are to be used only by the patient for whom it is prescribed. Do not share it with other people. The safety of treating an average of more than 4 headaches in a 30 day period has not been established. Imitrex Sumatriptan is the generic brand takes these headaches away in 15-30 minutes. Never fails. It's a miracle drug for anyone with these headaches. Store Imitrex spray between 36 and 86 degrees F 2 and 30 degrees C. Store away from heat, moisture, and light. Do not freeze. Do not store at temperatures above 86 degrees F 30 degrees C. Do not store in the bathroom. Keep Imitrex spray in the case provided. Throw away expired medicine as directed by your doctor the expiration date is printed on the treatment pack. Keep Imitrex spray out of the reach of children and away from pets. Included as part of the PRECAUTIONS section. Rebound headaches were a problem in my teens. When Imitrex came out I was very impressed by how effective it was. I have been using it for about 10-12 years and I am now experiencing some problems with my migraines not easing up like they used too. Also, I have began to experience "leg migraines" with my regular migraines. They only react to the statdose injection. Anti-nausea medications. These drugs may help you absorb your pain medication. Before injecting IMITREX, check with your doctor on acceptable injection sites and see the instructions inside the carton on discarding empty syringes and reloading an autoinjector device. inam.info eulexin
Use before you start to use the IMITREX STATdose System. It is unknown what effect hemodialysis or peritoneal dialysis has on the serum concentrations of sumatriptan. If you have a higher risk for heart problems see Precautions your doctor may perform a heart exam before you start taking sumatriptan. Imitrex Injection. Such reactions can be life threatening or fatal. Serious and sometimes fatal brain blood vessel problems like stroke have rarely happened with Imitrex spray. Contact your doctor at once if you have confusion, one-sided weakness, or speech or vision changes. If you have taken more medicine than you have been told, contact either your doctor, hospital emergency department, or nearest poison control center immediately. Are you trying to become pregnant? The onset of symptoms usually occurs within minutes to hours of receiving a new or a greater dose of a serotonergic medication. Discontinue Imitrex Tablets if serotonin syndrome is suspected. IMITREX Injection and any ergotamine-containing or ergot-type medication like dihydroergotamine or methysergide should not be used within 24 hours of each other, nor should IMITREX Injection and another 5-HT 1 agonist. Sumatriptan belongs to a group of drugs called triptans. It affects a certain natural chemical serotonin that constricts blood vessels in the brain. It may also block other pain pathways in the brain. Discontinue IMITREX Injection if these disturbances occur. Have you had a stroke, transient ischemic attacks TIAs or Raynaud syndrome? Burns and scars have been reported on the skin where the transdermal iontophoretic transdermal system has been worn. These reports describe severe redness, pain, skin discoloration, blistering, and cracked skin. On June 13, 2016, the manufacturer of the patch suspended sales and distribution of the patch to investigate the cause of these reports. Side effects may go away after you take the medicine for a while. order now generic benemid visa
The effect of sumatriptan on the protein binding of other drugs has not been evaluated. Imitrex spray is to be used only by the patient for whom it is prescribed. Do not share it with other people. Do not dispose of your used sharps disposal container in your household trash unless your community guidelines permit this. Do not recycle your used sharps disposal container. IMITREX is not used to treat other types of headaches such as hemiplegic that make you unable to move on one side of your body or basilar rare form of migraine with aura migraines. MAO, predominantly the A isoenzyme. Throw away the seal. Open the lid over the Syringe Cartridge. HT1 agonists have not been clearly established. It is not known if IMITREX is safe and effective in children under 18 years of age. Cerebral hemorrhage, subarachnoid hemorrhage, and stroke have occurred with 5-HT1 treatment; some have resulted in fatalities. One case of sumatriptan-induced cortical stroke has been reported in a patient with sagittal sinus thrombosis. In some cases, it appears possible that the cerebrovascular events were primary, and the 5-HT1 agonist administered in the belief that presenting symptoms were due to migraine when they were not. Patients with migraine may also be at an increased risk of certain cerebrovascular events such as stroke, hemorrhage, and transient ischemic attacks.
Cluster Headache: The efficacy of IMITREX Injection in the acute treatment of cluster headache was demonstrated in 2 randomized, double-blind, placebo-controlled, 2-period crossover trials. Patients age 21 to 65 were enrolled and were instructed to treat a moderate to very severe headache within 10 minutes of onset. Headache relief was defined as a reduction in headache severity to mild or no pain. In both trials, the proportion of individuals gaining relief at 10 or 15 minutes was significantly greater among patients receiving 6 mg of IMITREX Injection compared to those who received placebo see Table 3. One study evaluated a 12-mg dose; there was no statistically significant difference in outcome between patients randomized to the 6- and 12-mg doses. Significant elevation in blood pressure, including hypertensive crisis with acute impairment of organ systems, has been reported on rare occasions in patients treated with 5-HT 1 agonists, including patients without a history of hypertension. Monitor blood pressure in patients treated with IMITREX. Imitrex Injection is contraindicated in patients with uncontrolled hypertension. Follow all directions on the product package. The abuse potential of IMITREX Injection cannot be fully delineated in advance of extensive marketing experience. Never use more than your recommended dose. Overuse of migraine headache medicine can make headaches worse. buy abilify walmart
Food and Drug Administration. WebMD does not endorse any specific product, service, or treatment. Before having surgery, tell your doctor or dentist about all the products you use including prescription drugs, nonprescription drugs, and herbal products. Medicines are sometimes prescribed for purposes other than those listed in Patient Information leaflets. Do not use Imitrex for a condition for which it was not prescribed. Do not give Imitrex to other people, even if they have the same symptoms you have. It may harm them. Certain conditions can increase your risk for heart problems. Tell your doctor if you have any of these conditions, including: high blood pressure, high cholesterol, diabetes, family history of heart disease, overweight, smoker, postmenopausal women age more than 40 years men. Retrace your steps if you can't remember why you went into a room. Local irritative symptoms were reported in clinical trials with sumatriptan nasal spray in approximately 5% of patients, and were severe in about 1% of cases. Symptoms were noted as being transient and generally resolved in less than 2 hours. It is recommended that patients who are intermittent long-term users of sumatriptan and who have or acquire risk factors predictive of CAD, as described above, undergo periodic interval cardiovascular evaluation as they continue to use sumatriptan. In considering this recommendation for periodic cardiovascular evaluation, it is noted that patients with cluster headache are predominantly male and over 40 years of age, which are risk factors for CAD. Corneal Opacities: Sumatriptan causes corneal opacities and defects in the corneal epithelium in dogs; this raises the possibility that these changes may occur in humans. This medication may make you more sensitive to the sun. Limit your time in the sun. Avoid tanning booths and sunlamps. Use and wear protective clothing when outdoors. For subcutaneous injection only. The studies did not establish the efficacy of sumatriptan nasal spray compared to placebo in the treatment of migraine in adolescents. Adverse events observed in these clinical trials were similar in nature to those reported in clinical trials in adults. IMITREX and certain other medicines can affect each other, causing serious side effects. Loi V, Lai M, Pisano MR, Delzompo M "Sumatriptan and panic-like symptoms. That evening, every time I had to go to the bathroom, the headache would return. After taking an anti-diarrhea medication the next day, I thought I had escaped the headaches. Use lists, notes, and other helpful devices as reminders. warfarin
Put the Pen in the open Cartridge Pack. Urogenital: Rare were dysuria, frequency, dysmenorrhea, and renal calculus. Know the medicines you take. Keep a list of them to show your healthcare provider or pharmacist when you get a new medicine. This product is safe to take during when used as directed. Certain spinal cord may be prevented by maintaining adequate amounts of during pregnancy. Consult your doctor or pharmacist for details. IMITREX Injection should only be used where a clear diagnosis of migraine or cluster headache has been established. The prescriber should be aware that cluster headache patients often possess one or more predictive risk factors for coronary artery disease CAD. Morgan DR, Trimble M, McVeigh GE "Atrial fibrillation associated with sumatriptan. Imitrex, AMERGE, and TREXIMET are registered trademarks of the GlaxoSmithKline group of companies. The other brands listed are trademarks of their respective owners and are not trademarks of GlaxoSmithKline. The makers of these brands are not affiliated with and do not endorse GlaxoSmithKline or its products. Sumatriptan is injected under the skin. You may be shown how to use injections at home. Do not give yourself this medicine if you do not understand how to use the injection and properly dispose of used needles and syringes. Use Imitrex spray with caution in the ELDERLY; the risk of serious side effects eg, heart problems, high blood pressure may be increased. If so, is this a level of dehydration that I cannot manage on my own? Do not consider WebMD User-generated content as medical advice. Never delay or disregard seeking professional medical advice from your doctor or other qualified healthcare provider because of something you have read on WebMD. You should always speak with your doctor before you start, stop, or change any prescribed part of your care plan or treatment. WebMD understands that reading individual, real-life experiences can be a helpful resource but it is never a substitute for professional medical advice, diagnosis, or treatment from a qualified health care provider. If you think you may have a medical emergency, call your doctor or dial 911 immediately.
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Do not use IMITREX Injection if you are pregnant, think you might be pregnant, are trying to become pregnant, or are not using adequate contraception, unless you have discussed this with your doctor. Remember, if you answered YES to any of the above questions, then discuss it with your doctor. If you miss a dose of Imitrex tablets and you still have a headache, follow your doctor's dosing instructions. Contact your doctor immediately if you are unsure of what to do if you miss a dose. Do not take Imitrex tablets more often than prescribed. Do not take 2 doses at once. IMITREX STAT dose System NDC 0173-0478-00. dicyclomine order now mastercard usa
ZecuityR was voluntarily withdrawn from the market by the manufacturer in June 2016 due to reports of serious application site reactions associated with use of this iontophoretic transdermal system. Since marketing of the patch in September 2015, there have been a number of reports in which patients describe severe redness, cracked skin, blistering or welts, and burns or scars where the patch was worn. Many report resolution within hours to weeks, although there are reports of unresolved skin reactions, typically skin discoloration. The use of Imitrex Tablets is contraindicated in patients with ischemic or vasospastic CAD. There have been rare reports of serious cardiac adverse reactions, including acute myocardial infarction, occurring within a few hours following administration of Imitrex Tablets. Some of these reactions occurred in patients without known CAD.
You can take it as a pill or as a suppository if nausea or vomiting stops you from keeping anything down. Another form of ergotamine, called DHE 45 also treats them. You can get it as an injection or as a nasal spray. How should I store Imitrex Injection? Your healthcare provider may change your dose. Do not change your dose without first talking to your healthcare provider. The figure uses Kaplan-Meier product limit Survivorship Plot. vasotec mail order online canada
Men get them more than women do. You usually start getting them before you're age 30. Cluster headaches may disappear completely go into remission for months or years, but they can come back without any warning. Treatment of acute cluster headache with sumatriptan. the sumatriptan cluster headache study group. The incidence of adverse reactions in controlled clinical trials was not affected by gender or age of the patients. There were insufficient data to assess the impact of race on the incidence of adverse reactions. Tell your healthcare provider about all the medicines you take, including prescription and nonprescription medicines, vitamins, and herbal supplements. clopidogrel